Choosing a Skeletal Muscle Relaxant
The incidence of drowsiness, the most frequent adverse reaction, was similar with both drugs. Addiction Resource is an educational platform for sharing and disseminating information about addiction and substance abuse recovery centers. Addiction Resource is not a healthcare provider, nor does it claim to offer sound medical advice to anyone.
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Of note, methocarbamol costs substantially less than metaxalone. Baclofen is one of the most powerful centrally acting muscle relaxants. It is usually indicated in patients with spasticity such as cerebral palsy or multiple sclerosis.
Other uses for this medicine
Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding.
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However, mixing them and using them together would be unwise and may lead to dangerous and devastating effects. Cyclobenzaprine warnings, comprising the effects of using each of these medications on their own include a slowing of the mental faculties, drowsiness, lightheadedness, and lowered motor coordination. When used together, these effects may be exacerbated, increasing the risk of an accident.
More About Drugs and Medications
As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment. There are many ways you can add physical flexeril.live activity to your healthy lifestyle, no matter your age or activity level. Physical activity related questions will be answered by one of HealthLink BC’s qualified exercise professionals.
- Patients with low back pain or fibromyalgia may benefit from treatment with cyclobenzaprine.
- It helps relieve pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles.
- Seizures should be controlled with benzodiazepines or, if these are ineffective, other anticonvulsants (e.g. phenobarbital, phenytoin).
- Cyclobenzaprine may interact with monoamine oxidase inhibitors and should not be used concurrently or within 14 days of discontinuation of these drugs.
- Drowsiness, dizziness, dry mouth, constipation, or tiredness may occur.
Like the TCAs, cyclobenzaprine has anticholinergic properties and may cause dry mouth, blurred vision, increased intraocular pressure, urinary retention, and constipation. The drug should, therefore, be used with caution in individuals with angle-closure glaucoma or prostatic hypertrophy. As with other TCAs, cyclobenzaprine should not be used in patients with cardiac arrhythmias, conduction disturbances, or congestive heart failure or during the acute phase of recovery from myocardial infarction. Cyclobenzaprine may interact with monoamine oxidase inhibitors and should not be used concurrently or within 14 days of discontinuation of these drugs. Withdrawal symptoms consisting of nausea, headache, and malaise have been reported following abrupt cessation of cyclobenzaprine after prolonged use. Whether cyclobenzaprine is superior to other drugs for the management of acute myofascial strain is unclear and it usually adds more side effects with little therapeutic gain (Turturro et al 2003).
There is also evidence that cyclical antidepressants may decrease the seizure threshold by interfering with chloride conductance on the GABA receptor. It is available in immediate-release tablets of 5 milligrams, 7.5 milligrams, and 10 milligrams and extended-release capsules of 15 milligrams and 30 milligrams and is usually given three times daily. The extended-release formulation should be administered at the same time each day. The capsule may be swallowed whole, but its contents also may be sprinkled onto a tablespoon of applesauce for immediate consumption without chewing the granules. The patient should rinse their mouth to ensure that they have swallowed all the contents.
If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles.
The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Using Flexeril with other drugs that make you drowsy can worsen this effect.
Protect the patient’s airway, establish an intravenous line and initiate gastric decontamination. Observation with cardiac monitoring and observation for signs of CNS or respiratory depression, hypotension, cardiac dysrhythmias and/or conduction blocks, and seizures is necessary. If signs of toxicity occur at any time during this period, extended monitoring is required. Monitoring of plasma drug levels should not guide management of the patient. Dialysis is probably of no value because of low plasma concentrations of the drug. In the higher dose groups this microscopic change was seen after 26 weeks and even earlier in rats which died prior to 26 weeks; at lower doses, the change was not seen until after 26 weeks.
